Last year’s beaten finalists, Tuchel has reached the final game of every cup competition he’s entered in since replacing Frank Lampard and this is another favourable fixture.
Having beaten non-league Chesterfield in the last round, playing a League One team at home will be seen as a very decent chance to make it into the next round. Kick-off is set for 12.30pm GMT.
Here’s everything you need to know about where to watch the game...
Where to watch Chelsea vs Plymouth Argyle
TV channel: The game will be broadcast on the BBC via their red button service.
Live stream: Both the BBC iPlayer and the BBC Sport website will offer live streams.
Live blog: You can follow all of the action with Standard Sport’s dedicated LIVE match blog. James Robson will be providing updates.